Program Summary

Program Summary

The overall goals for the EHS CC Program are to enhance the capabilities of existing programs in environmental health sciences, assist with building programmatic and scientific capacity, lead in the development of novel research directions, recruit and groom future leaders in the field, and pioneer efforts in community engagement. The EHS CC grant provides facilities and resources to accelerate research along the spectrum from basic mechanistic and toxicological science to population and public health and dissemination.


An EHS CC should support innovation and be on the cutting edge of science. It is expected that research activities will cross a variety of disciplines to bring multiple perspectives and approaches to bear on significant problems. It is expected that the interdisciplinary nature of an EHS CC will have a synergestic effect that results in greater depth, breadth, quality, innovation and productivity beyond what individual scientists would be likely to attain by working independently. The EHS CC grant provides facilities and resources to accelerate research along the spectrum from basic mechanistic and toxicological science to population and public health and dissemination. While the EHS CC grant provides support for core resources and facilities, it does not provide direct funding for research projects, although limited funds are provided for pilot projects.


The sponsor is looking for the following in an application:


Does the EHS CC address an important problem or a critical barrier to progress in the field? Is there a strong scientific premise for the project? If the aims of the EHS CC  are achieved, how will scientific knowledge, technical capability, and/or clinical practice be improved? How will successful completion of the aims change the concepts, methods, technologies, treatments, services, or preventative interventions that drive this field?

Are the EHS CC’s plans targeted toward building research capacity?  Will the plans, as proposed, attract investigators to the EHS CC from within and outside environmental health sciences?  Will the research supported by the EHS CC likely contribute to understanding of environmental health sciences and, ultimately, public health?


Are the PD(s)/PI(s), collaborators, and other researchers well suited to the project? If Early Stage Investigators or New Investigators, or in the early stages of independent careers, do they have appropriate experience and training? If established, have they demonstrated an ongoing record of accomplishments that have advanced their field(s)? If the project is collaborative or multi-PD/PI, do the investigators have complementary and integrated expertise; are their leadership approach, governance and organizational structure appropriate for the project?

Do the Center Director and Core leaders demonstrate the ability to provide scientific and administrative leadership and direction? Does the application indicate that the Director has the authority to appoint new members to the EHS CC and discontinue membership status, when appropriate? Is the Deputy Director qualified to serve in the absence of the Director? 


Does the application challenge and seek to shift current research or clinical practice paradigms by utilizing novel theoretical concepts, approaches or methodologies, instrumentation, or interventions? Are the concepts, approaches or methodologies, instrumentation, or interventions novel to one field of research or novel in a broad sense? Is a refinement, improvement, or new application of theoretical concepts, approaches or methodologies, instrumentation, or interventions proposed?   


Are the overall strategy, methodology, and analyses well-reasoned and appropriate to accomplish the specific aims of the EHS CC? Have the investigators presented strategies to ensure a robust and unbiased approach, as appropriate for the work proposed?  Are potential problems, alternative strategies, and benchmarks for success presented? If the project is in the early stages of development, will the strategy establish feasibility and will particularly risky aspects be managed? Have the investigators presented adequate plans to address relevant biological variables, such as sex, for studies in vertebrate animals or human subjects?

If the EHS CC involves human subjects and/or NIH-defined clinical research, are the plans to address 1) the protection of human subjects from research risks, and 2) inclusion (or exclusion) of individuals on the basis of sex/gender, race, and ethnicity, as well as the inclusion or exclusion of children, justified in terms of the scientific goals and research strategy proposed?     


Will the scientific environment in which the work will be done contribute to the probability of success? Are the institutional support, equipment and other physical resources available to the investigators adequate for the project proposed? Will the project benefit from unique features of the scientific environment, subject populations, or collaborative arrangements?

Does the EHS CC demonstrate that it includes the skills, technologies, and capacity to foster interdisciplinary, state-of-the-art, and innovative research that would lead to important discoveries or major scientific advances in the chosen areas of focus? Are the size and breadth of the research grant base in the EHS CC directly relevant to environmental health sciences and to the theme of the EHS CC placing special emphasis on NIEHS-supported grants? Does the EHS CC take advantage of the capability of its research base to maximize scientific productivity, particularly through interdisciplinary coordination and collaboration?  

Application Limits

Application Limits

University is limited to one proposal.

Additional Information


UIC Letter of Intent
March 17, 2017
UIC Internal Competition
Sponsor Letter of Intent
Sponsor Application
May 17, 2017

Letter of Intent

Letter of Intent

Letter of Intent (LOI) Form


Depending upon the number of LOIs submitted, OVCR might be required to facilitate an internal peer review process to select UIC’s submission(s) to this program.  White paper instructions will distributed to those who have submitted LOIs.


Please contact Natalia Glubisz at or 312-996-8348 with any questions.


If an authorized principal investigator is not listed above, please consider the limited competition still open. Contact for further information.